KAT7-acetylated YBX1 promotes hepatocellular carcinoma proliferation by reprogramming nucleotide metabolism
Our findings highlight that KAT7 acetylates YBX1 and promotes HCC progression by reprogramming nucleotide metabolism, offering therapeutic implications.
Authors
- Pengyu Chen (ORCID: https://orcid.org/0000-0002-3706-103X)
- Xun Li (ORCID: https://orcid.org/0000-0002-3513-5904)
- He Huang (ORCID: https://orcid.org/0009-0006-6650-2507)
- Haiping Wang (ORCID: https://orcid.org/0000-0002-5114-8860)
- Shang Li (ORCID: https://orcid.org/0000-0003-4363-0902)
- Yongqiang Zhou
- Longfei Ren
- Haixia Zhao (ORCID: https://orcid.org/0000-0003-3330-2083)
Institutions
- Second Military Medical University (CN)
- Eastern Hepatobiliary Surgery Hospital (CN)
- First Hospital of Lanzhou University (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-02-21
- DOI
- https://doi.org/10.1186/s12885-025-13708-w
- Citations
- 3
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 2.42