Ferroptosis-related genes in preeclampsia: integrative bioinformatics analysis, experimental validation and drug prediction
This study identified four FRGs as potential PE biomarkers and therapeutic targets, providing new insights into PE pathogenesis through integrated bioinformatics and experimental validation. These findings may facilitate early PE diagnosis and treatment development.
Authors
- Jianbo Wu (ORCID: https://orcid.org/0000-0003-3319-9717)
- Feng Zhan (ORCID: https://orcid.org/0000-0002-8714-9590)
- Lidan He (ORCID: https://orcid.org/0000-0002-7418-6886)
- Xuemei Li (ORCID: https://orcid.org/0000-0001-5455-121X)
- Huijuan Yang (ORCID: https://orcid.org/0000-0001-5355-1170)
Institutions
- Fujian Medical University (CN)
- Fujian Jiangxia University (CN)
- First Affiliated Hospital of Fujian Medical University (CN)
- Taiyuan University of Science and Technology (CN)
Publication Details
- Journal
- BMC Pregnancy and Childbirth
- Published
- 2025-02-21
- DOI
- https://doi.org/10.1186/s12884-025-07325-5
- Citations
- 5
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 10.29
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Fujian Province
- Fujian Provincial Health Technology Project