DEAE-cellulose based ultrathin layer chromatography – mass spectrometry for protein separation and characterization
This work illustrates the capability of DEAE-cellulose UTLC plates in protein separation and the feasibility of combining nanofiber UTLC with paper spray MS for further characterization. Successful characterization of both monomeric and complex proteins was obtained using this MS ionization methodology where charge state distributions of proteins showed effective performance of our UTLC separation procedure.
Authors
- Abraham K. Badu‐Tawiah (ORCID: https://orcid.org/0000-0001-8642-3431)
- Anpu Wang
- Susan V. Olesik (ORCID: https://orcid.org/0000-0001-7757-5150)
- Taghi Sahraeian (ORCID: https://orcid.org/0000-0002-4393-1708)
Institutions
- The Ohio State University (US)
Publication Details
- Journal
- Analytica Chimica Acta
- Published
- 2025-02-21
- DOI
- https://doi.org/10.1016/j.aca.2025.343832
- Citations
- 2
- Primary Topic
- Advanced Cellulose Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.19
Funders
- U.S. Department of Energy
- Ohio State University
- National Institutes of Health
- National Institute of General Medical Sciences
- Basic Energy Sciences