Cefotaxime-Resistant <i>Neisseria meningitidis</i> Sequence Type 4821 Causing Fulminant Meningitis
We explored the role of commensal Neisseria in the emergence of third-generation cephalosporin-resistant N. meningitidis. Cefotaxime resistance-conferring penA795 was prevalent among commensal Neisseria isolates in Shanghai, China, and was acquired by a serogroup C quinolone-resistant sequence type 4821 N. meningitidis, Nm507, causing fulminant meningitis in an unvaccinated 2-year-old child.
Authors
- Mei Zeng (ORCID: https://orcid.org/0000-0002-3491-5298)
- Yohei Doi (ORCID: https://orcid.org/0000-0002-9620-2525)
- Qinglan Guo (ORCID: https://orcid.org/0000-0003-2490-1201)
- Minggui Wang (ORCID: https://orcid.org/0000-0001-7682-5859)
- Youxing Shao
- Min Chen
- Mingliang Chen (ORCID: https://orcid.org/0000-0002-2707-9471)
- Jiehao Cai
Publication Details
- Journal
- Emerging infectious diseases
- Published
- 2025-02-21
- DOI
- https://doi.org/10.3201/eid3103.241493
- Citations
- 3
- Primary Topic
- Bacterial Infections and Vaccines
- Type
- article
- Field-Weighted Citation Impact
- 3.55