Outbreak Caused by Multidrug-Resistant <i>Mycobacterium Tuberculosis</i> with Unusual Combination of Resistance Mutations, Northern Argentina, 2006–2022
To reconstruct transmission chains of the multidrug-resistant tuberculosis Ch strain, which harbors a unique combination of resistance mutations, we analyzed genomes of 25 isolates from 12 patients with diagnosis during 2006-2022 in Chaco Province, Argentina. Amplification of resistance, high mortality rates, and indications of a wider outbreak raise concerns for surveillance programs.
Authors
- Darı́o Garcı́a de Viedma (ORCID: https://orcid.org/0000-0003-3647-7110)
- Laura Pérez‐Lago (ORCID: https://orcid.org/0000-0001-5249-7619)
- Norma González González (ORCID: https://orcid.org/0000-0002-9689-527X)
- Domingo Palmero (ORCID: https://orcid.org/0000-0002-7496-5492)
- David Couvin (ORCID: https://orcid.org/0000-0002-7897-9023)
- Silvia Altabe (ORCID: https://orcid.org/0000-0002-5059-7568)
- Nalin Rastogi (ORCID: https://orcid.org/0000-0002-7199-7747)
- Federico Lorenzo (ORCID: https://orcid.org/0009-0005-3622-4000)
- Noemí Yokobori (ORCID: https://orcid.org/0000-0001-8966-0491)
- Ana Gamberale
- M. Alegre (ORCID: https://orcid.org/0000-0002-9741-3711)
- Roxana Paul
- Norberto Símboli (ORCID: https://orcid.org/0000-0002-7887-1362)
- Beatriz López
Publication Details
- Journal
- Emerging infectious diseases
- Published
- 2025-02-21
- DOI
- https://doi.org/10.3201/eid3103.241272
- Citations
- 3
- Primary Topic
- Mycobacterium research and diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 4.06