Predecompression and postdecompression cognitive and affective changes in Chiari malformation type I
The authors demonstrate significant, often unrecognized, impairments in cognitive function and psychiatric symptoms in a cohort of CM-I patients. Following targeted surgical posterior fossa decompression, these symptoms improved, suggesting that at least in a subgroup of symptomatic CM-I patients, these symptoms may be treatable. This study highlights the potential role of the cerebellum in cognitive and psychiatric dysfunction.
Authors
- Kamil W. Nowicki (ORCID: https://orcid.org/0000-0002-7378-3195)
- J. Bret Crittenden
- Tina L. Stephenson
- Amy L. Byrd (ORCID: https://orcid.org/0000-0002-7930-6832)
- Michael M. McDowell
- Yue-Fang Chang
- Robert M. Friedlander (ORCID: https://orcid.org/0000-0003-4423-9219)
- Peter L. Strick (ORCID: https://orcid.org/0000-0001-5794-8458)
- Rohit Mantena
- Ricardo J. Fernández-de Thomas (ORCID: https://orcid.org/0000-0002-5210-8748)
- Luke C. Henry (ORCID: https://orcid.org/0000-0003-4557-0309)
Institutions
- University of Pittsburgh (US)
- Evans Army Community Hospital (US)
- Neurological Surgery (US)
- Chatham University (US)
Publication Details
- Journal
- Journal of neurosurgery
- Published
- 2025-02-21
- DOI
- https://doi.org/10.3171/2024.8.jns241363
- Citations
- 2
- Primary Topic
- Spinal Dysraphism and Malformations
- Type
- article
- Field-Weighted Citation Impact
- 3.76