Anti‐Müllerian hormone for assessing ovarian toxicity of cancer treatment in young women: It’s complicated

The rising incidence of cancer among young women highlights the importance of understanding treatment‐related gonadotoxicity, which can lead to infertility and long‐term health complications from premature estrogen decline. Although anti‐Müllerian hormone is considered the most reliable indicator of ovarian reserve, its interpretation among oncology patients is complex because it is dependent on the treatment modality, necessitating further research to fully understand the impact of specific treatments on anti‐Müllerian hormone and to identify alternative markers to reliably assess the ovarian toxicity of newer cancer therapies.

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Publication Details

Journal
Cancer
Published
2025-02-20
DOI
https://doi.org/10.1002/cncr.35774
Primary Topic
Ovarian function and disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Anti‐Müllerian hormone for assessing ovarian toxicity of cancer treatment in young women: It’s complicated

Kimia Sorouri, Kathryn J. Ruddy, Ann H. Partridge, Karen Glass et al.
1 links
Cancer
Ovarian function and disorders
article

Anti‐Müllerian hormone for assessing ovarian toxicity of cancer treatment in young women: It’s complicated

Kimia Sorouri, Kathryn J. Ruddy, Ann H. Partridge, Karen Glass, Ellen Warner
article en

Abstract

The rising incidence of cancer among young women highlights the importance of understanding treatment‐related gonadotoxicity, which can lead to infertility and long‐term health complications from premature estrogen decline. Although anti‐Müllerian hormone is considered the most reliable indicator of ovarian reserve, its interpretation among oncology patients is complex because it is dependent on the treatment modality, necessitating further research to fully understand the impact of specific treatments on anti‐Müllerian hormone and to identify alternative markers to reliably assess the ovarian toxicity of newer cancer therapies.

CancerVol. 131(5)
Sunnybrook Health Science Centre (CA), Mayo Clinic (US), Harvard University (US), University of Alberta (CA), University of Toronto (CA), Dana-Farber Cancer Institute (US), CReATe Fertility Centre (CA), Dana-Farber Brigham Cancer Center (US)
Good health and well-being
Openalex Percentile: Top 95%
Ovarian function and disorders
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Anti‐Müllerian hormone for assessing ovarian toxicity of cancer treatment in young women: It’s complicated — Kimia Sorouri, Kathryn J. Ruddy, et al. · Cancer (2025) | TGRS Research Map | TGRS