Design of fish-scale microstructured stents and their biomechanical effects on cerebral aneurysm

The addition of microstructures to the inner surface of the stent reduces resistance and inhibits the phenomenon of blood adhesion. In this study, the design of a fish-scale microstructured vascular stent was proposed based on bionics, and its main design parameters were optimized using the finite element method. In addition, the hemodynamic effects of a standard stent and a fish-scale microstructured stent on an ideal cerebral aneurysm were comparatively analyzed. The results showed that the fish-scale microstructured stent significantly accelerated intraluminal blood flow velocity by 11.6% compared to the standard stent. In addition, the fish-scale microstructured stent was able to reduce blood flow into the aneurysm lumen by 28.6%.

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Publication Details

Journal
Computer Methods in Biomechanics & Biomedical Engineering
Published
2025-02-21
DOI
https://doi.org/10.1080/10255842.2025.2465343
Citations
1
Primary Topic
Intracranial Aneurysms: Treatment and Complications
Type
article
Field-Weighted Citation Impact
1.39

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article

Design of fish-scale microstructured stents and their biomechanical effects on cerebral aneurysm

Qingli Zheng, Boya Liu, Xiaogang Wu, Yongwang Zhao et al.
1 citations
Computer Methods in Biomechanics & Biomedical Engineering
Intracranial Aneurysms: Treatment and Complications
1.39
article

Design of fish-scale microstructured stents and their biomechanical effects on cerebral aneurysm

Qingli Zheng, Boya Liu, Xiaogang Wu, Yongwang Zhao, Dong Ma, Cungen Ma, Meng Zhang, Yonghong Wang, Aohua Zhang, Xuanze Fan, Lijuan Song, Yanru Xue
article en
1 citations

Abstract

The addition of microstructures to the inner surface of the stent reduces resistance and inhibits the phenomenon of blood adhesion. In this study, the design of a fish-scale microstructured vascular stent was proposed based on bionics, and its main design parameters were optimized using the finite element method. In addition, the hemodynamic effects of a standard stent and a fish-scale microstructured stent on an ideal cerebral aneurysm were comparatively analyzed. The results showed that the fish-scale microstructured stent significantly accelerated intraluminal blood flow velocity by 11.6% compared to the standard stent. In addition, the fish-scale microstructured stent was able to reduce blood flow into the aneurysm lumen by 28.6%.

Computer Methods in Biomechanics & Biomedical Engineering
Shanxi Medical University (CN), Shanxi University (CN), State Administration of Traditional Chinese Medicine of the People's Republic of China (CN), China National Pharmaceutical Group Corporation (China) (CN), Shanxi Provincial Children's Hospital (CN), Shanxi Academy of Medical Sciences (CN), Shanxi Provincial People’s Hospital (CN), Taiyuan University of Technology (CN)
National Natural Science Foundation of China, China Postdoctoral Science Foundation, Shanxi Scholarship Council of China, Natural Science Foundation of Shanxi Province
Life below water
Openalex Percentile: Top 23%
Intracranial Aneurysms: Treatment and Complications
1.39
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