ChIP provides 10-fold microbial DNA enrichment from tissue while minimizing bias
We recommend ChIP in situations where host depletion is important but where minimizing taxonomic bias is essential, and the MolYsis or Zymo kit for situations where host depletion level is more important than taxonomic bias.
Authors
- Austin D. Swafford (ORCID: https://orcid.org/0000-0001-5655-8300)
- Se Jin Song (ORCID: https://orcid.org/0000-0003-0750-5709)
- Caitlin Guccione (ORCID: https://orcid.org/0000-0002-0446-1635)
- Andrew P. Bartko (ORCID: https://orcid.org/0000-0002-1237-2747)
- Rob Knight (ORCID: https://orcid.org/0000-0002-0975-9019)
- Lucas Patel (ORCID: https://orcid.org/0000-0001-8607-2782)
- Sydney Lavoie (ORCID: https://orcid.org/0000-0003-2890-3634)
- Michelle Rooks
- Jon G. Sanders (ORCID: https://orcid.org/0000-0001-6077-4014)
- Shrikant S. Bhute (ORCID: https://orcid.org/0000-0003-1576-3548)
- Antonio G. González (ORCID: https://orcid.org/0000-0003-3925-5986)
Institutions
- Pfizer (United States) (US)
- University of California San Diego (US)
- University of California San Diego Medical Center (US)
- La Jolla Bioengineering Institute (US)
Publication Details
- Journal
- Molecular Biology Reports
- Published
- 2025-02-21
- DOI
- https://doi.org/10.1007/s11033-025-10330-8
- Citations
- 4
- Primary Topic
- Mycobacterium research and diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 5.42
Funders
- Pfizer
- Merck KGaA
- National Institutes of Health
- University of California, San Diego
- National Institute of General Medical Sciences