The efferocytosis dilemma: how neutrophil extracellular traps and PI3K/Rac1 complicate diabetic wound healing
Targeting NETs and the PI3K/Rac1 pathway emerges as a potential therapeutic strategy to enhance healing in diabetic wounds by promoting macrophage efferocytosis.
Authors
- Yunlong Fan (ORCID: https://orcid.org/0000-0002-2647-9609)
- Jiaman Yang
- Rongya Yang (ORCID: https://orcid.org/0000-0001-8201-9394)
- Yulin Xie
- He Zhu (ORCID: https://orcid.org/0000-0001-5107-7575)
Institutions
- Chinese PLA General Hospital (CN)
- Zhujiang Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2025-02-21
- DOI
- https://doi.org/10.1186/s12964-025-02092-4
- Citations
- 11
- Primary Topic
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 8.77
Funders
- National Natural Science Foundation of China