Critical Role of p38α MAPK Subclass in the Development of Pain Hypersensitivity After Hind Paw Incision
These results demonstrated the distinct roles of p38 MAPK subclasses in the DRG, with p38α MAPK playing a dominant role in the development of pain hypersensitivity after tissue injury. Targeting p38α MAPK might be a promising therapeutic strategy for managing postoperative pain.
Authors
- Daiki Ishikawa
- Fumimasa Amaya (ORCID: https://orcid.org/0000-0003-2934-0845)
- Kentaro Oh‐hashi (ORCID: https://orcid.org/0000-0002-3438-2102)
- Shunsuke Yamakita (ORCID: https://orcid.org/0000-0002-8533-6763)
Institutions
- Kyoto Prefectural University of Medicine (JP)
- Gifu University (JP)
Publication Details
- Journal
- Journal of Pain Research
- Published
- 2025-02-01
- DOI
- https://doi.org/10.2147/jpr.s488494
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Society for the Promotion of Science