Role and Mechanism of Mitochondrial Ribosomal Proteins in Septic Myocardial Injury
The findings suggest that both MRPS16 and MRPL47 can mitigate mitochondrial injury by attenuating mitochondrial biosynthesis dysfunction, energy metabolism disorders, and Ca<sup>2+</sup> disturbances caused by septic myocardial injury. This ultimately reduces cellular damage and alleviates septic myocardial injury.
Authors
- Longfei Wu (ORCID: https://orcid.org/0000-0002-0954-9126)
- Xiaoqin Mao (ORCID: https://orcid.org/0000-0002-3022-9063)
- Junchao Huang (ORCID: https://orcid.org/0000-0003-1066-3206)
- Xiongfei Jia
Institutions
- First People's Hospital of Yunnan Province (CN)
- Second People's Hospital of Yunnan Province (CN)
- People's Liberation Army 401 Hospital (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-02-01
- DOI
- https://doi.org/10.2147/jir.s495987
- Citations
- 2
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.71