Retrograde aortic access for ventricular arrhythmia ablation: A novel plug and suture strategy for vascular closure

The retrograde aortic (RA) approach is frequently utilized for catheter ablation targeting ventricular arrhythmia (VA).Various sheath types may be used for RA access, including deflectable and nondeflectable sheaths with larger diameters.Deflectable sheaths offer an additional pivot point, potentially enhancing stability and contact in regions with challenging catheter positioning, especially with irregular anatomy.However, registry studies have demonstrated that the risk of complications during VA ablations is substantial, with a significant proportion attributable to vascular access. 1 Consequently, there is a need for novel hemostasis methods following sheaths removal, especially when using deflectable sheaths with large-bore access, to reduce vascular complications and improve patient outcomes.Current options for achieving hemostasis following femoral arterial access include manual compression and the use of vascular closure devices (VCDs).Insights from structural heart interventions, such as transcatheter aortic valve replacement, have contributed to advancements in safe RA access techniques.Recently, a novel technique combining a plug-based with a suture-based VCD has been described. 2This novel VCD strategy has not been tested in the VA ablation population, in which anticoagulation is uninterrupted.This study aimed to evaluate the safety and efficacy of the novel VCD strategy for large-bore vascular access following transfemoral VA ablation.

Authors

Institutions

Publication Details

Journal
Heart Rhythm O2
Published
2025-02-21
DOI
https://doi.org/10.1016/j.hroo.2025.02.009
Primary Topic
Cardiac Arrhythmias and Treatments
Type
article
Field-Weighted Citation Impact
0.00

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Retrograde aortic access for ventricular arrhythmia ablation: A novel plug and suture strategy for vascular closure

Philipp Krisai, Behnam Subin, Felix Mahfoud, Nicolas Schärli et al.
Heart Rhythm O2
Cardiac Arrhythmias and Treatments
article

Retrograde aortic access for ventricular arrhythmia ablation: A novel plug and suture strategy for vascular closure

Philipp Krisai, Behnam Subin, Felix Mahfoud, Nicolas Schärli, Michael Kühne, Patrick Badertscher, Sven Knecht, Christian Sticherling, Rebecca Arnet
article en

Abstract

The retrograde aortic (RA) approach is frequently utilized for catheter ablation targeting ventricular arrhythmia (VA).Various sheath types may be used for RA access, including deflectable and nondeflectable sheaths with larger diameters.Deflectable sheaths offer an additional pivot point, potentially enhancing stability and contact in regions with challenging catheter positioning, especially with irregular anatomy.However, registry studies have demonstrated that the risk of complications during VA ablations is substantial, with a significant proportion attributable to vascular access. 1 Consequently, there is a need for novel hemostasis methods following sheaths removal, especially when using deflectable sheaths with large-bore access, to reduce vascular complications and improve patient outcomes.Current options for achieving hemostasis following femoral arterial access include manual compression and the use of vascular closure devices (VCDs).Insights from structural heart interventions, such as transcatheter aortic valve replacement, have contributed to advancements in safe RA access techniques.Recently, a novel technique combining a plug-based with a suture-based VCD has been described. 2This novel VCD strategy has not been tested in the VA ablation population, in which anticoagulation is uninterrupted.This study aimed to evaluate the safety and efficacy of the novel VCD strategy for large-bore vascular access following transfemoral VA ablation.

Heart Rhythm O2Vol. 6(5)
University Hospital of Basel (CH)
National Science Foundation, Amgen, Pfizer, AstraZeneca, Foundation for Cardiovascular Research, Universität Basel, Boston Scientific Corporation, Freiwillige Akademische Gesellschaft, ReCor Medical, European Commission, Deutsche Forschungsgemeinschaft, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, Schweizerische Herzstiftung, Deutsche Herzstiftung, Servier, MicroPort, Biosense Webster, Daiichi Sankyo Europe
Zero hunger
Openalex Percentile: Top 95%
Cardiac Arrhythmias and Treatments
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.