Evaluation of target temperature on effectiveness of myocardial preservation during hypothermic machine perfusion
HOP for 12 hours had better heart function preservation than SCS for 6 hours. Even HNOP had similar results compared to SCS. Greater edema formation in ESHP hearts did not affect heart function. Hypothermic ESHP safely enhances function preservation compared to SCS.
Authors
- Benjamin Adam (ORCID: https://orcid.org/0000-0003-1908-1739)
- Sanaz Hatami (ORCID: https://orcid.org/0000-0002-6792-6620)
- Parichehr Hassanzadeh (ORCID: https://orcid.org/0000-0001-7465-2640)
- Guilherme Mainardi Aguiar da Silva (ORCID: https://orcid.org/0009-0006-3293-0976)
- Mitchell J. Wagner (ORCID: https://orcid.org/0000-0002-5883-6340)
- Jayan Nagendran (ORCID: https://orcid.org/0000-0001-5827-9823)
- Darren H. Freed
- Xiuhua Wang (ORCID: https://orcid.org/0000-0002-0557-3962)
Institutions
- University of Alberta (CA)
- Alberta Biodiversity Monitoring Institute (CA)
- Canadian VIGOUR Centre (CA)
- Translational Research in Oncology (CA)
Publication Details
- Journal
- JHLT Open
- Published
- 2025-02-21
- DOI
- https://doi.org/10.1016/j.jhlto.2025.100234
- Citations
- 2
- Primary Topic
- Cardiac Ischemia and Reperfusion
- Type
- article
- Field-Weighted Citation Impact
- 2.94