The Research Progress of T Lymphocytes in Myocardial Infarction.
Myocardial infarction is a severe clinical manifestation of acute coronary syndrome.Despite advancements in early treatment, the long-term impact of ischemia-related heart damage remains a major cause of heart failure.The immune response plays a role in cardiac complications following myocardial infarction.T lymphocytes exhibit different phenotypes after myocardial infarction.CD4 T cells differentiate into multiple subsets, contributing to immune regulation, promoting angiogenesis, regulating scar formation, and influencing cardiac remodeling.CD8 T cells are primarily cytotoxic and may directly kill cardiomyocytes, promoting adverse ventricular remodeling in myocardial infarction.Understanding the role of T cells at each stage of myocardial infarction could identify potential targets for developing new treatments
Authors
- Junqiang Liu (ORCID: https://orcid.org/0000-0002-7677-4155)
- Hao Li (ORCID: https://orcid.org/0000-0003-2832-4851)
- Shufeng Zhong (ORCID: https://orcid.org/0009-0007-5307-8572)
Publication Details
- Journal
- Research Review
- Published
- 2025-02-20
- DOI
- https://doi.org/10.52845/cs/2024-4-6-7
- Primary Topic
- Atherosclerosis and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00