The Research Progress of T Lymphocytes in Myocardial Infarction.

Myocardial infarction is a severe clinical manifestation of acute coronary syndrome.Despite advancements in early treatment, the long-term impact of ischemia-related heart damage remains a major cause of heart failure.The immune response plays a role in cardiac complications following myocardial infarction.T lymphocytes exhibit different phenotypes after myocardial infarction.CD4 T cells differentiate into multiple subsets, contributing to immune regulation, promoting angiogenesis, regulating scar formation, and influencing cardiac remodeling.CD8 T cells are primarily cytotoxic and may directly kill cardiomyocytes, promoting adverse ventricular remodeling in myocardial infarction.Understanding the role of T cells at each stage of myocardial infarction could identify potential targets for developing new treatments

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Publication Details

Journal
Research Review
Published
2025-02-20
DOI
https://doi.org/10.52845/cs/2024-4-6-7
Primary Topic
Atherosclerosis and Cardiovascular Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

The Research Progress of T Lymphocytes in Myocardial Infarction.

Junqiang Liu, Hao Li, Shufeng Zhong
Research Review
Atherosclerosis and Cardiovascular Diseases
article

The Research Progress of T Lymphocytes in Myocardial Infarction.

Junqiang Liu, Hao Li, Shufeng Zhong
article en

Abstract

Myocardial infarction is a severe clinical manifestation of acute coronary syndrome.Despite advancements in early treatment, the long-term impact of ischemia-related heart damage remains a major cause of heart failure.The immune response plays a role in cardiac complications following myocardial infarction.T lymphocytes exhibit different phenotypes after myocardial infarction.CD4 T cells differentiate into multiple subsets, contributing to immune regulation, promoting angiogenesis, regulating scar formation, and influencing cardiac remodeling.CD8 T cells are primarily cytotoxic and may directly kill cardiomyocytes, promoting adverse ventricular remodeling in myocardial infarction.Understanding the role of T cells at each stage of myocardial infarction could identify potential targets for developing new treatments

Research Review
Openalex Percentile: Top 96%
Atherosclerosis and Cardiovascular Diseases
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The Research Progress of T Lymphocytes in Myocardial Infarction. — Junqiang Liu, Hao Li, et al. · Research Review (2025) | TGRS Research Map | TGRS