Analysis of thyroid carcinoma composition and spatial architecture in the progression of dedifferentiation, lymphatic metastasis, and gastric metastasis
These findings highlight the dynamic changes in cell composition, intercellular communication, and potential markers associated with TC dedifferentiation and distant metastasis. Further research based on our findings may contribute to improving diagnostic and therapeutic strategies for patients with TC.
Authors
- Hao Wang (ORCID: https://orcid.org/0000-0003-1452-3956)
- Huabao Xiong (ORCID: https://orcid.org/0000-0003-0180-2104)
- Yun Lin (ORCID: https://orcid.org/0000-0003-1379-9301)
- Fenglian Yan (ORCID: https://orcid.org/0000-0003-1698-8271)
- Ruichun Lu
- Di Wang (ORCID: https://orcid.org/0000-0001-9597-4745)
Institutions
- Qingdao University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- Affiliated Hospital of Qingdao University (CN)
- Qingdao Municipal Hospital (CN)
- Jining Medical University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-02-21
- DOI
- https://doi.org/10.1186/s12967-025-06252-5
- Citations
- 1
- Primary Topic
- Thyroid Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.29
Funders
- National Natural Science Foundation of China