Circulating inflammatory cytokines and risk of aortic stenosis: A Mendelian randomization analysis
Our research enhances the current understanding of the role of specific inflammatory biomarker pathways in aortic stenosis. Nevertheless, further validation is required to assess the viability of targeting these cytokines through pharmacological or lifestyle interventions as potential treatments for aortic stenosis.
Authors
- Luying Cao
- Congyi Cheng
- Zhenwei Chen (ORCID: https://orcid.org/0000-0002-6360-0455)
- Ning Wang (ORCID: https://orcid.org/0000-0003-1745-1425)
- Cong Su (ORCID: https://orcid.org/0000-0003-0450-9317)
- Wang Fen (ORCID: https://orcid.org/0000-0001-9451-0578)
- Yu Zhang (ORCID: https://orcid.org/0000-0002-7384-0778)
- Wenqiang Chen (ORCID: https://orcid.org/0000-0002-0350-1383)
- Jijun Wu (ORCID: https://orcid.org/0000-0001-9118-6258)
- Junlin Teng (ORCID: https://orcid.org/0000-0002-7611-0631)
- Xiaohan Qiu (ORCID: https://orcid.org/0009-0005-3737-7981)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Zhongshan People's Hospital (CN)
- Ministry of Education (BD)
- Qilu Hospital of Shandong University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Cytokine
- Published
- 2025-02-21
- DOI
- https://doi.org/10.1016/j.cyto.2025.156887
- Citations
- 1
- Primary Topic
- Atherosclerosis and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.80