The Association Between Statin Drugs and Rhabdomyolysis: An Analysis of FDA Adverse Event Reporting System (FAERS) Data and Transcriptomic Profiles
Simvastatin was associated with the highest risk of rhabdomyolysis. The risk of rhabdomyolysis was more pronounced in men than women. Several possible DDIs were identified including furosemide/Lasix, allopurinol clopidogrel/Plavix, and pantoprazole.
Authors
- Feng Cheng (ORCID: https://orcid.org/0000-0003-3619-8090)
- Weiru Han (ORCID: https://orcid.org/0000-0002-6264-3090)
- Paula Vélez (ORCID: https://orcid.org/0000-0001-9394-2547)
- S. M. Wood
- Madison Martin
- Robert Morris (ORCID: https://orcid.org/0000-0002-6994-0602)
- Jacob Ward
- Kun Bu (ORCID: https://orcid.org/0009-0006-9526-3023)
- Ariana Crescitelli
Institutions
- University of South Florida (US)
Publication Details
- Journal
- Genes
- Published
- 2025-02-21
- DOI
- https://doi.org/10.3390/genes16030248
- Citations
- 9
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 18.06