Aggressive Head and Neck Squamous Cell Carcinoma in the Setting of <i>GATA2</i> Deficiency
This case highlights the aggressive nature of SCC in the context of GATA2 deficiency and underscores the importance of genetic testing in patients with unusual malignancy presentations and suspected immunodeficiency. Genetic testing in the patient's children allows for early diagnosis of GATA2 deficiency and provides an opportunity for curative intervention through hematopoietic stem cell transplantation.
Authors
- James A. Stewart (ORCID: https://orcid.org/0000-0002-0976-2349)
- Kirk Withrow
- Carissa M. Thomas (ORCID: https://orcid.org/0000-0003-0765-5731)
- Brejjette Aljabi
Institutions
- University of Alabama at Birmingham (US)
Publication Details
- Journal
- Head & Neck
- Published
- 2025-02-21
- DOI
- https://doi.org/10.1002/hed.28117
- Primary Topic
- Immunodeficiency and Autoimmune Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00