Early vaccine effectiveness estimates against medically attended laboratory-confirmed influenza based on influenza surveillance, Beijing, China, 2024/25 season

We estimated early influenza vaccine effectiveness (VE) for the 2024/25 season in outpatients, in Beijing using a test-negative design. A(H1N1)pdm09 dominated (99.3%), all sequenced strains (n = 38) clustered in clade 6B.1A.5a.2a, and 37 of 38 antigenically similar to the vaccine strain. VE against any influenza virus infection was 48.5% (95% CI: 34.8-59.5) and 48.7% (95% CI: 35.1-59.7) against A(H1N1)pdm09. Vaccination in the current or previous season against any influenza showed a VE of 52.5% to 54.9%, compared to no vaccination in both seasons.

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Publication Details

Journal
Eurosurveillance
Published
2025-02-20
DOI
https://doi.org/10.2807/1560-7917.es.2025.30.7.2500084
Citations
8
Primary Topic
Influenza Virus Research Studies
Type
article
Field-Weighted Citation Impact
10.83
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article

Early vaccine effectiveness estimates against medically attended laboratory-confirmed influenza based on influenza surveillance, Beijing, China, 2024/25 season

Daitao Zhang, Jiaxin Ma, Peng Yang, Wei Duan et al.
8 citations
Eurosurveillance
Influenza Virus Research Studies
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article

Early vaccine effectiveness estimates against medically attended laboratory-confirmed influenza based on influenza surveillance, Beijing, China, 2024/25 season

Daitao Zhang, Jiaxin Ma, Peng Yang, Wei Duan, Dan Wu, Zhaomin Feng, Yingying Wang, Lu Zhang, Jia Li, Jiaojiao Zhang, Quanyi Wang, Chunna Ma, Xiaodi Hu, Ying Sun, Weixian Shi, Li Zhang
article en
8 citations

Abstract

We estimated early influenza vaccine effectiveness (VE) for the 2024/25 season in outpatients, in Beijing using a test-negative design. A(H1N1)pdm09 dominated (99.3%), all sequenced strains (n = 38) clustered in clade 6B.1A.5a.2a, and 37 of 38 antigenically similar to the vaccine strain. VE against any influenza virus infection was 48.5% (95% CI: 34.8-59.5) and 48.7% (95% CI: 35.1-59.7) against A(H1N1)pdm09. Vaccination in the current or previous season against any influenza showed a VE of 52.5% to 54.9%, compared to no vaccination in both seasons.

EurosurveillanceVol. 30(7)
Capital Medical University (CN), Beijing Center for Disease Prevention and Control (CN)
Good health and well-being
Openalex Percentile: Top 2%
Influenza Virus Research Studies
10.83
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