Influenza vaccine effectiveness against detected infection in the community, France, October 2024 to February 2025
Influenza circulates at high levels in Europe since November 2024. Using a test-negative study based on data from French community laboratories between October 2024 and February 2025, we estimated vaccine effectiveness (VE) against PCR-detected influenza infection (44,420/15,052; positive/negative individuals). For all age groups, the overall VE was 42% (95% CI: 37-46%), with 26% (95% CI: 18-34%) against influenza A and 75% (95% CI: 66-82%) against influenza B. Among individuals ≥ 65-year-olds VE was 22% (95% CI: 13-30%) and among 0-64-year-olds, 60% (95% CI: 56-65%).
Authors
- Thomas Duret
- François Blanquart (ORCID: https://orcid.org/0000-0003-0591-2466)
- A Jacques (ORCID: https://orcid.org/0000-0003-4665-6462)
- Marta Coelho Nunes (ORCID: https://orcid.org/0000-0003-3788-878X)
- Vincent Enouf (ORCID: https://orcid.org/0000-0001-7609-4742)
- Bruno Lina (ORCID: https://orcid.org/0000-0002-8959-2123)
- Antonin Bal (ORCID: https://orcid.org/0000-0002-0261-2495)
- Laurence Josset (ORCID: https://orcid.org/0000-0002-7158-1186)
- Vincent Vieillefond
- Claire Nour Abou Chakra (ORCID: https://orcid.org/0000-0002-3345-0580)
- Stéphanie Haïm‐Boukobza
- Benoit Visseaux
- Marie Anne Rameix-Welti
- Guillaume Deleglise
- Valentin Wehrle
Institutions
- Université Claude Bernard Lyon 1 (FR)
- South African Medical Research Council (ZA)
- École Normale Supérieure de Lyon (FR)
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Institut Pasteur (FR)
- Collège de France (FR)
- University of the Witwatersrand (ZA)
- Université de Versailles Saint-Quentin-en-Yvelines (FR)
- Université Paris Cité (FR)
- Université Paris Sciences et Lettres (FR)
- Hospices Civils de Lyon (FR)
- Centre Interdisciplinaire de Recherche en Biologie (FR)
- Virologie et Pathologies Humaines (FR)
- The Design Knowledge Company (United States) (US)
- Centre International de Recherche en Infectiologie (FR)
- Infection et inflammation (FR)
- Virbac (France) (FR)
Publication Details
- Journal
- Eurosurveillance
- Published
- 2025-02-20
- DOI
- https://doi.org/10.2807/1560-7917.es.2025.30.7.2500074
- Citations
- 6
- Primary Topic
- Influenza Virus Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 8.13