Tumor Microenvironment Modulation by Tumor-Associated Macrophages: Implications for Neoadjuvant Chemotherapy Response in Breast Cancer
This study highlights the critical role of TAMs dynamics in shaping NAC response in BC. Notably, CD163+ TAMs may emerge as pivotal players in mechanisms of chemotherapy resistance and response, underscoring their potential as biomarkers and therapeutic targets in breast cancer treatment.
Authors
- Peter A. van Dam (ORCID: https://orcid.org/0000-0002-9184-7703)
- Nuh Zafer Cantürk (ORCID: https://orcid.org/0000-0002-0042-9742)
- Zwi Berneman (ORCID: https://orcid.org/0000-0002-9133-4588)
- Christophe Van Berckelaer (ORCID: https://orcid.org/0000-0003-4082-9799)
- Wiebren A.A. Tjalma (ORCID: https://orcid.org/0000-0002-6618-045X)
- Gizem Öner (ORCID: https://orcid.org/0000-0003-0162-2752)
- Senada Koljenović (ORCID: https://orcid.org/0000-0002-5185-3455)
- Gayathri R. Devi (ORCID: https://orcid.org/0000-0001-9158-7289)
- Sevilay Altıntaş
- M. Praet (ORCID: https://orcid.org/0009-0004-8847-432X)
- Hans Stoop
Institutions
- University of Antwerp (BE)
- Duke University (US)
- Antwerp University Hospital (BE)
- Kocaeli Üniversitesi (TR)
Publication Details
- Journal
- Breast Cancer Targets and Therapy
- Published
- 2025-02-01
- DOI
- https://doi.org/10.2147/bctt.s493085
- Citations
- 1
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- Kocaeli Üniversitesi