Biomarkers: New Advances in Diabetic Nephropathy

Diabetic nephropathy (DN) is the leading cause of uremia and clinical mortality, characterized by the progressive deterioration of kidney structure and function due to prolonged exposure to hyperglycemia. This condition often necessitates renal replacement therapy for patients with end-stage-renal-disease (ESRD). Consequently, early detection, diagnosis, and treatment of DN are crucial to mitigate disease progression, enhance patient outcomes, and maintain a good quality of life. Exploring relevant biomarkers for the early diagnosis of DN holds significant importance. In recent years, numerous researchers have identified various novel biomarkers associated with diabetic nephropathy, which are critical for predicting both the onset and progression of the disease. This article aims to provide a comprehensive overview of the biomarkers related to DN.