Re‐evaluating prognostic indicators: The critical role of body composition and gene expression in endometrial cancer outcomes
BMI alone is not a significant prognostic factor in endometrial cancer. Comprehensive assessments of BC, gene expression profiles, and the TME provide more accurate prognostic information and highlight potential therapeutic targets. These findings advocate for a shift towards personalized medicine, incorporating detailed phenotyping and molecular profiling to improve patient outcomes.
Authors
- Ignacio Wichmann (ORCID: https://orcid.org/0000-0002-1115-2937)
- Fernán Gómez‐Valenzuela (ORCID: https://orcid.org/0000-0001-6889-976X)
- Sumie Kato
- Nicolás Rubio Sáez
- Enrique Ossandón
- Mauricio A. Cuello (ORCID: https://orcid.org/0000-0003-2812-0015)
- Carolina Ibáñez (ORCID: https://orcid.org/0000-0001-7254-0653)
- Elisa Orlandini (ORCID: https://orcid.org/0000-0002-6582-7733)
- Jorge Brañes
Institutions
- Universidad Mayor (CL)
- Pontificia Universidad Católica de Chile (CL)
- Hospital Clínico de la Universidad Católica (CL)
- Advanced Center for Chronic Diseases (CL)
- Stanford University (US)
Publication Details
- Journal
- International Journal of Gynecology & Obstetrics
- Published
- 2025-02-21
- DOI
- https://doi.org/10.1002/ijgo.70016
- Primary Topic
- Endometrial and Cervical Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Consejo Nacional de Innovación, Ciencia y Tecnología
- Fondo de Financiamiento de Centros de Investigación en Áreas Prioritarias