Total lesion glycolysis of primary tumor and lymphnodes is a strong predictor for development of distant metastases in oropharyngeal carcinoma patients with independent validation in automatically delineated lesions
TLG<sub>all</sub> is a promising biomarker to select OPC patients with high risk for metachronous distant metastases.
Authors
- Joanna Kaźmierska (ORCID: https://orcid.org/0000-0001-7160-8150)
- Daniel Zips (ORCID: https://orcid.org/0000-0001-5779-9675)
- Carmen Stromberger (ORCID: https://orcid.org/0000-0001-6165-1729)
- Sebastian Zschaeck (ORCID: https://orcid.org/0000-0003-3109-0662)
- Pavel Nikulin (ORCID: https://orcid.org/0000-0002-4568-4018)
- Mechthild Krause (ORCID: https://orcid.org/0000-0003-1776-9556)
- Marina Hajiyianni
- Paulina Cegła (ORCID: https://orcid.org/0000-0002-6676-3436)
- Claus Belka (ORCID: https://orcid.org/0000-0002-1287-7825)
- Patrick Hausmann
- Witold Cholewiński
- Adrien Holzgreve (ORCID: https://orcid.org/0000-0002-9566-8438)
- Jörg van den Hoff (ORCID: https://orcid.org/0000-0003-4039-4780)
- Frank Hofheinz (ORCID: https://orcid.org/0000-0001-8016-4643)
- Iosif Strouthos (ORCID: https://orcid.org/0000-0001-6229-5471)
- Christian Furth (ORCID: https://orcid.org/0000-0001-7302-7886)
- Michaël Baumann (ORCID: https://orcid.org/0000-0002-9340-974X)
- Guillaume Landry (ORCID: https://orcid.org/0000-0003-1707-4068)
- Emily Kukuk
- Elia Lombardo (ORCID: https://orcid.org/0000-0003-4522-8298)
- Jörg Kotzerke
Institutions
- Poznan University of Medical Sciences (PL)
- German Cancer Research Center (DE)
- European University Cyprus (CY)
- Max Delbrück Center (DE)
- Heidelberg University (DE)
- Helmholtz-Zentrum Dresden-Rossendorf (DE)
- University Hospital Heidelberg (DE)
- LMU Klinikum (DE)
- Humboldt-Universität zu Berlin (DE)
- German Cancer Society (DE)
- Greater Poland Cancer Center (PL)
- German Center for Infection Research (DE)
- German Centre for Cardiovascular Research (DE)
- OncoRay (DE)
- Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE)
- University Hospital Carl Gustav Carus (DE)
- Deutsches Konsortium für Translationale Krebsforschung (DE)
- Freie Universität Berlin (DE)
- Technische Universität Dresden (DE)
- Charité - Universitätsmedizin Berlin (DE)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Cancer Imaging
- Published
- 2025-02-21
- DOI
- https://doi.org/10.1186/s40644-025-00836-6
- Citations
- 1
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.85
Funders
- Bundesministerium für Bildung und Forschung
- Charité – Universitätsmedizin Berlin