Melatonin Regulates Glymphatic Function to Affect Cognitive Deficits, Behavioral Issues, and Blood–Brain Barrier Damage in Mice After Intracerebral Hemorrhage: Potential Links to Circadian Rhythms

Melatonin and luzindole treatment affect GS function, BBB permeability, and cognitive-behavioral outcomes in mice with ICH. The underlying mechanism may involve the regulation of circadian rhythms.

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Publication Details

Journal
CNS Neuroscience & Therapeutics
Published
2025-02-01
DOI
https://doi.org/10.1111/cns.70289
Citations
12
Primary Topic
Cerebrospinal fluid and hydrocephalus
Type
article
Field-Weighted Citation Impact
10.91
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article

Melatonin Regulates Glymphatic Function to Affect Cognitive Deficits, Behavioral Issues, and Blood–Brain Barrier Damage in Mice After Intracerebral Hemorrhage: Potential Links to Circadian Rhythms

Yunzhao Chen, Huifang Guo, Shanjun Wang, Zengguang Wang et al.
12 citations
CNS Neuroscience & Therapeutics
Cerebrospinal fluid and hydrocephalus
10.91
article

Melatonin Regulates Glymphatic Function to Affect Cognitive Deficits, Behavioral Issues, and Blood–Brain Barrier Damage in Mice After Intracerebral Hemorrhage: Potential Links to Circadian Rhythms

Yunzhao Chen, Huifang Guo, Shanjun Wang, Zengguang Wang, Jing Li, Yuheng Liu, Anqi He, Junjie Gong, Xinguo Sun, Mingyu Zhao
article en
12 citations

Abstract

Melatonin and luzindole treatment affect GS function, BBB permeability, and cognitive-behavioral outcomes in mice with ICH. The underlying mechanism may involve the regulation of circadian rhythms.

CNS Neuroscience & TherapeuticsVol. 31(2)
Tianjin Medical University General Hospital (CN), Binzhou People's Hospital (CN), Yidu Central Hospital of Weifang (CN), Inner Mongolia People's Hospital (CN)
Openalex Percentile: Top 1%
Cerebrospinal fluid and hydrocephalus
10.91
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