Vancomycin dosing design method considering risk factors for nephrotoxicity
In the present study, the risk of nephrotoxicity for each AUCss was quantitatively analyzed using logistic regression curves for the High- and Low-risk groups. This allowed for the proposal of strategic individual target concentrations based on the balance between risk and benefit.
Authors
- Yoshihiko MATSUKI
- Ken-ichi Sako (ORCID: https://orcid.org/0000-0003-1486-5825)
- Y. Kozima
- Mayu Yanagi
- Shigekazu Watanabe
- Tamaki Watanabe
- Nobuhiro Yasuno
Institutions
- Nihon Pharmaceutical University (JP)
- Teikyo University Hospital (JP)
- Teikyo University (JP)
Publication Details
- Journal
- Journal of Pharmaceutical Health Care and Sciences
- Published
- 2025-02-21
- DOI
- https://doi.org/10.1186/s40780-025-00416-7
- Citations
- 2
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 2.79