Mitigation of Renal Injury in Wistar Rats Using Adipose Tissue-derived Mesenchymal Stromal Cells and Simvastatin
What's known on the subject? and What does the study add?Ischemia-reperfusion injury (IRI) remains one of the primary risk factors contributing to adverse outcomes in kidney transplantation.Combining adipose-derived mesenchymal stem cells and simvastatin enhances renal function after IRI, indicating synergy.Neutrophil gelatinase-associated lipocalin was identified as a potential early biomarker for renal IRI.
Authors
- Sérgio Adriane Bezerra de Moura (ORCID: https://orcid.org/0000-0002-8204-3244)
- Letícia Fracaro (ORCID: https://orcid.org/0000-0003-3464-777X)
- Alexandra Cristina Senegaglia (ORCID: https://orcid.org/0000-0002-8052-6357)
- Cármen Lúcia Kuniyoshi Rebelatto (ORCID: https://orcid.org/0000-0003-1407-0416)
- Fernando Meyer (ORCID: https://orcid.org/0000-0003-4503-3319)
- Paulo Roberto Slud Brofman (ORCID: https://orcid.org/0000-0001-6401-782X)
- Flávio Lobo Heldwein (ORCID: https://orcid.org/0000-0003-4321-0078)
- Roberto Pecoits-Filho
- Daniela Boccasanta
Publication Details
- Journal
- Journal of Urological Surgery
- Published
- 2025-02-21
- DOI
- https://doi.org/10.4274/jus.galenos.2024.2024-10-2
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00