Causal Association Between Microbiome and Oral-Oropharyngeal Cancer: A Mendelian Randomization Study
Our MR study indicates that the oral microbiota has a significant causal impact on the risk of oral and oropharyngeal cancers. The microbial biomarkers we identified, which are linked to OOPSCC, have the potential to uncover the underlying mechanisms and pave the way for new therapeutic approaches for targeted treatment of these malignancies.
Authors
- Xufeng Huang (ORCID: https://orcid.org/0000-0001-9941-3355)
- Divya Gopinath (ORCID: https://orcid.org/0000-0002-4279-7420)
- Zhengrui Li (ORCID: https://orcid.org/0000-0003-4923-0088)
- Qi Wang (ORCID: https://orcid.org/0009-0000-0757-3627)
Institutions
- University of Debrecen (HU)
- Ajman University (AE)
- Shanghai Jiao Tong University (CN)
- Ruijin Hospital (CN)
- Shanghai Stomatological Hospital (CN)
- Shanghai Ninth People's Hospital (CN)
Publication Details
- Journal
- International Dental Journal
- Published
- 2025-02-21
- DOI
- https://doi.org/10.1016/j.identj.2025.01.017
- Citations
- 7
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 6.55