Improvement of atopic dermatitis-like symptoms in a murine model via the chromogranin A-derived peptide catestatin
Collectively, these findings suggest CST as a promising therapeutic agent for AD, capable of enhancing skin barrier function, modulating immune responses, and targeting the Notch1/PKC pathway, offering a novel approach to AD treatment focusing on barrier restoration and immune modulation.
Authors
- Yi Jayne Tan (ORCID: https://orcid.org/0000-0003-1486-4734)
- Wanchen Zhao
- Shigaku Ikeda (ORCID: https://orcid.org/0000-0002-7520-0707)
- Quan Sun (ORCID: https://orcid.org/0000-0001-8324-2803)
- François Niyonsaba (ORCID: https://orcid.org/0000-0002-0588-8315)
- Arisa Ikeda
- Ko Okumura (ORCID: https://orcid.org/0000-0003-3238-6422)
- Shan Wang (ORCID: https://orcid.org/0000-0002-0273-8397)
- Mengyao Yang (ORCID: https://orcid.org/0000-0003-2414-6584)
- Ge Peng (ORCID: https://orcid.org/0000-0002-3278-2604)
- Alafate Abudouwanli
- Hideoki Ogawa
Institutions
- Juntendo University (JP)
- Beijing Children’s Hospital (CN)
- China Medical University (CN)
Publication Details
- Journal
- Allergology International
- Published
- 2025-02-21
- DOI
- https://doi.org/10.1016/j.alit.2025.01.001
- Citations
- 3
- Primary Topic
- Dermatology and Skin Diseases
- Type
- article
- Field-Weighted Citation Impact
- 6.01