Distinct Alterations of Inflammatory Biomarkers in Cluster Headache: A Case Control Study
Findings show that the immune system is altered in all 3 states of cluster headache compared with controls. Oncostatin m was elevated, constituting a promising target for future studies. The distinct alterations between episodic and chronic cluster headache are striking and urges further research of the immune system in cluster headache to better understand its potential role in prediction of disease activity and treatment response. ANN NEUROL 2025;98:4-18.
Authors
- Agneta Snoer
- Thomas Folkmann Hansen (ORCID: https://orcid.org/0000-0001-6703-7762)
- Nunu Lund (ORCID: https://orcid.org/0000-0003-3062-030X)
- Rigmor Jensen (ORCID: https://orcid.org/0000-0001-6433-5887)
- Connar Stanley James Westgate (ORCID: https://orcid.org/0000-0001-5066-8306)
- M. Søborg (ORCID: https://orcid.org/0000-0001-6015-6814)
- Anja Sofie Petersen (ORCID: https://orcid.org/0000-0002-0125-6038)
Institutions
- University of Copenhagen (DK)
- Lundbeck (Denmark) (DK)
- Glostrup Hospital (DK)
- Rigshospitalet (DK)
- Danish Multiple Sclerosis Center (DK)
Publication Details
- Journal
- Annals of Neurology
- Published
- 2025-02-21
- DOI
- https://doi.org/10.1002/ana.27205
- Citations
- 3
- Primary Topic
- Migraine and Headache Studies
- Type
- article
- Field-Weighted Citation Impact
- 4.41