3D joint T <sub>1</sub> /T <sub>1</sub> <sub>ρ</sub> /T <sub>2</sub> mapping and water‐fat imaging for contrast‐agent free myocardial tissue characterization at 1.5T
The proposed approach enables simultaneous 3D whole-heart joint <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:semantics> <mml:mrow> <mml:msub><mml:mrow><mml:mi>T</mml:mi></mml:mrow> <mml:mrow><mml:mn>1</mml:mn></mml:mrow> </mml:msub> </mml:mrow> <mml:annotation>$$ {T}_1 $$</mml:annotation></mml:semantics> </mml:math> / <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:semantics> <mml:mrow> <mml:msub><mml:mrow><mml:mi>T</mml:mi></mml:mrow> <mml:mrow><mml:mn>1</mml:mn> <mml:mi>ρ</mml:mi></mml:mrow> </mml:msub> </mml:mrow> <mml:annotation>$$ {T}_{1\rho } $$</mml:annotation></mml:semantics> </mml:math> / <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:semantics> <mml:mrow> <mml:msub><mml:mrow><mml:mi>T</mml:mi></mml:mrow> <mml:mrow><mml:mn>2</mml:mn></mml:mrow> </mml:msub> </mml:mrow> <mml:annotation>$$ {T}_2 $$</mml:annotation></mml:semantics> </mml:math> mapping and water/fat imaging in <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:semantics><mml:mrow><mml:mo>≈</mml:mo></mml:mrow> <mml:annotation>$$ \approx $$</mml:annotation></mml:semantics> </mml:math> 7 min scan time, demonstrating good agreement with conventional mapping techniques in phantoms and healthy subjects and promising results in 1 patient with suspected cardiovascular disease.
Authors
- Karl Kunze (ORCID: https://orcid.org/0000-0001-6403-2712)
- Claudia Prieto (ORCID: https://orcid.org/0000-0003-4602-2523)
- Donovan Tripp (ORCID: https://orcid.org/0000-0002-6113-2563)
- Simon Littlewood (ORCID: https://orcid.org/0000-0001-7433-1409)
- René M. Botnar (ORCID: https://orcid.org/0000-0003-2811-2509)
- Anastasia Fotaki (ORCID: https://orcid.org/0000-0002-0353-5778)
- Michael Crabb (ORCID: https://orcid.org/0000-0002-7919-9731)
Institutions
- Pontificia Universidad Católica de Chile (CL)
- King's College London (GB)
- Siemens (United Kingdom) (GB)
- Institute for Advanced Study (DE)
- Millennium Institute for Integrative Biology (CL)
- Technical University of Munich (DE)
Publication Details
- Journal
- Magnetic Resonance in Medicine
- Published
- 2025-02-21
- DOI
- https://doi.org/10.1002/mrm.30397
- Primary Topic
- Cardiac Imaging and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute for Health and Care Research
- British Heart Foundation
- Engineering and Physical Sciences Research Council
- Institute for Advanced Study, Technische Universität München
- Centre For Medical Engineering, King’s College London
- Fondo Nacional de Desarrollo Científico y Tecnológico