Caffeine Intoxication in Which the Theophylline Level Served as an Indicator of the Treatment Course and the Caffeine Level Could Be Measured

We thank the authors for their interest in our article and thoughtful comments.Just as you have said, caffeine can be consumed daily, and it seems that the consumption of caffeinated beverages by young people, especially athletes and healthcare workers, is indeed increasing.Athletes in particular may be motivated by factors such as increased energy and improved performance, while healthcare workers may be influenced by long and irregular working hours and demanding nature.Although moderate caffeine intake is generally considered safe for most people, its excessive intake can lead to addiction.Symptoms of poisoning are wide-ranging and include effects on the central nervous system, circulatory system, respiratory system, digestive system, renal endocrine system, and skeletal muscle system.In severe cases, symptoms include headaches, insomnia, nausea, arrhythmia, and convulsions, which can be fatal.Therefore, we would like to spread awareness about the possibility of caffeine poisoning from drinking water containing caffeine and the symptoms of poisoning.If caffeine poisoning is suspected, it is important to determine the amount ingested.Measuring caffeine and theophylline concentrations is a very effective tool for the management and treatment of patients with addiction and for verifying the effectiveness of treatment.