Atypical Mpox Cutaneous Presentation After Full Vaccination

In 2022-2023 mpox outbreak led to declaration of a public health emergency. Smallpox vaccination has led to increased immunity and a decrease in clinical disease. The role of vaccination in immunosuppressed patients is not well understood. We present an atypical case of cutaneous mpox, presenting in a fully vaccinated, immunosuppressed, HIV-negative patient as an initial isolated, subcutaneous neck mass. We review the diagnostic dilemma and workup for these atypical cases.

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Publication Details

Journal
American Journal of Dermatopathology
Published
2025-02-19
DOI
https://doi.org/10.1097/dad.0000000000002945
Citations
2
Primary Topic
Poxvirus research and outbreaks
Type
article
Field-Weighted Citation Impact
2.07
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article

Atypical Mpox Cutaneous Presentation After Full Vaccination

Jason Zucker, Benjamin A. Miko, Joyeeta G. Dastidar, Megan H. Trager et al.
2 citations
American Journal of Dermatopathology
Poxvirus research and outbreaks
2.07
article

Atypical Mpox Cutaneous Presentation After Full Vaccination

Jason Zucker, Benjamin A. Miko, Joyeeta G. Dastidar, Megan H. Trager, Celine M. Schreidah, Stephanie M. Gallitano, Blair A. Jenkins, Alexandra J. Coromilas, Sameera Husain
article en
2 citations

Abstract

In 2022-2023 mpox outbreak led to declaration of a public health emergency. Smallpox vaccination has led to increased immunity and a decrease in clinical disease. The role of vaccination in immunosuppressed patients is not well understood. We present an atypical case of cutaneous mpox, presenting in a fully vaccinated, immunosuppressed, HIV-negative patient as an initial isolated, subcutaneous neck mass. We review the diagnostic dilemma and workup for these atypical cases.

American Journal of DermatopathologyVol. 47(5)
University of Michigan (US), Columbia University Irving Medical Center (US), Columbia University (US)
Good health and well-being
Openalex Percentile: Top 16%
Poxvirus research and outbreaks
2.07
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