Comparative efficacy of different antihypertensive drug classes for stroke prevention: A network meta-analysis of randomized controlled trials
These findings suggest that ACEIs, dihydropyridine CCBs, and thiazide-like diuretics may provide superior prevention against stroke, all-cause mortality, and cardiovascular mortality in hypertensive patients. Combinations of ACEIs and CCBs may provide enhanced protection of stroke than ACEIs or ARBs monotherapy.
Authors
- Zhong‐ning Zhu (ORCID: https://orcid.org/0000-0002-0281-3545)
- Xindi Ma (ORCID: https://orcid.org/0000-0001-7129-3814)
- Handong Wang (ORCID: https://orcid.org/0000-0001-5989-9338)
- Junxia Li (ORCID: https://orcid.org/0000-0001-5191-3166)
- Tao Ding (ORCID: https://orcid.org/0000-0002-7042-375X)
- Yuan Cheng (ORCID: https://orcid.org/0000-0003-4173-293X)
- Ding Yu
Institutions
- Hebei Medical University (CN)
- Fourth Hospital of Hebei Medical University (CN)
- Hebei University of Chinese Medicine (CN)
- First Affiliated Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-02-21
- DOI
- https://doi.org/10.1371/journal.pone.0313309
- Citations
- 5
- Primary Topic
- Blood Pressure and Hypertension Studies
- Type
- article
- Field-Weighted Citation Impact
- 6.94