Phototherapeutic keratectomy for calcific band keratopathy secondary to multiple myeloma

To report a case of calcific band keratopathy (CBK) secondary to multiple myeloma (MM) successfully treated with phototherapeutic keratectomy (PTK). An 80-year-old woman presented with progressive vision loss in her left eye with a best corrected visual acuity (BCVA) of 4/10 in the left eye (OS). Slit-lamp examination revealed a central band-like corneal opacification indicative of CBK. Anterior segment optical coherence tomography (AS-OCT) showed a subepithelial hyper reflective layer. Further evaluation confirmed an indolent IgAk MM, with no indication for systemic therapy. PTK was performed using the Technolas® TENEO™ 317 M2 excimer laser, resulting in corneal surface regularization and BCVA improvement. At 1-year follow-up, the patient was asymptomatic, had a clear cornea, normal topography, and a BCVA of 10/10. CBK can be associated with systemic conditions. PTK is an effective and safe procedure for managing CBK, and can provide complete visual rehabilitation.

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Publication Details

Journal
Journal of Surgical Case Reports
Published
2025-02-01
DOI
https://doi.org/10.1093/jscr/rjaf046
Primary Topic
Glaucoma and retinal disorders
Type
article
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article

Phototherapeutic keratectomy for calcific band keratopathy secondary to multiple myeloma

Ana Cardoso, Sandra Barros, Gonçalo Tardão, Nuno Campos et al.
Journal of Surgical Case Reports
Glaucoma and retinal disorders
article

Phototherapeutic keratectomy for calcific band keratopathy secondary to multiple myeloma

Ana Cardoso, Sandra Barros, Gonçalo Tardão, Nuno Campos, Filipe Moraes
article en

Abstract

To report a case of calcific band keratopathy (CBK) secondary to multiple myeloma (MM) successfully treated with phototherapeutic keratectomy (PTK). An 80-year-old woman presented with progressive vision loss in her left eye with a best corrected visual acuity (BCVA) of 4/10 in the left eye (OS). Slit-lamp examination revealed a central band-like corneal opacification indicative of CBK. Anterior segment optical coherence tomography (AS-OCT) showed a subepithelial hyper reflective layer. Further evaluation confirmed an indolent IgAk MM, with no indication for systemic therapy. PTK was performed using the Technolas® TENEO™ 317 M2 excimer laser, resulting in corneal surface regularization and BCVA improvement. At 1-year follow-up, the patient was asymptomatic, had a clear cornea, normal topography, and a BCVA of 10/10. CBK can be associated with systemic conditions. PTK is an effective and safe procedure for managing CBK, and can provide complete visual rehabilitation.

Journal of Surgical Case ReportsVol. 2025(2)
Hospital Garcia de Orta (PT)
Openalex Percentile: Top 94%
Glaucoma and retinal disorders
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