[Preliminary study on preparation of decellularized nerve grafts from GGTA1 gene-edited pigs and their immune rejection in xenotransplantation].
The decellularized nerve grafts from GGTA1 gene-edited pigs have well-preserved nerve structure, complete decellularization, retain the natural nerve basement membrane tube structure and components, and low immune response after xenotransplantation through <i>in vitro</i> experiments.
Authors
- Yan Shi (ORCID: https://orcid.org/0000-0001-9777-8836)
- Xiangyu Song
- Jiang Peng (ORCID: https://orcid.org/0000-0003-4662-9288)
- Xiangling Li (ORCID: https://orcid.org/0000-0002-8177-9719)
- Y. B. Liu (ORCID: https://orcid.org/0000-0002-8268-6792)
- Zhibo Jia
- Jinjuan Zhao
- Tieyuan Zhang (ORCID: https://orcid.org/0000-0002-6368-2606)
- Chaochao Li (ORCID: https://orcid.org/0000-0001-7536-0527)
- Ruichao He
Institutions
- Guiyang Medical University (CN)
- Chinese PLA General Hospital (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-02-15
- DOI
- https://doi.org/10.7507/1002-1892.202408052
- Primary Topic
- Tissue Engineering and Regenerative Medicine
- Type
- article