Neonatal cerebral venous sinus thrombosis in the setting of maternal SARS-CoV-2 infection: Case report

Coronavirus 19 disease (COVID-19) is a known risk factor for venous thromboembolism, and vertical transmission of SARS-CoV-2 has been shown to cause neurological insult to the developing fetus. We describe the case of a late preterm neonate with maternal history of third trimester COVID-19 who was found to have cerebral venous sinus thrombosis. We demonstrate for the first time an association between neonatal cerebral venous sinus thrombosis and placental abnormalities related to COVID-19 and posit this as a possible mechanistic link.