MRS and Optical Imaging Studies of Therapeutic Response to Combination Therapy Targeting BRAF/MEK in Murine Melanomas
MRS, ORI, and biochemical assays identified critical metabolic changes, highlighting potential biomarkers and supporting the integration of metabolic inhibitors with MAPK-targeted therapies to improve clinical outcomes.
Authors
- Fernando Arias‐Mendoza
- Pradeep Kumar Gupta (ORCID: https://orcid.org/0000-0002-4036-3899)
- Sanjeev Chawla (ORCID: https://orcid.org/0000-0001-6978-7284)
- Michael D. Farwell (ORCID: https://orcid.org/0000-0003-0650-4747)
- Skyler Nova
- Kavindra Nath (ORCID: https://orcid.org/0000-0002-3197-5703)
- David Nelson (ORCID: https://orcid.org/0009-0008-5993-8710)
- Stepan Orlovskiy (ORCID: https://orcid.org/0009-0001-7985-6025)
- Lin Z. Li (ORCID: https://orcid.org/0000-0001-9447-7982)
- Dinesh Kumar Singh
Institutions
- Norwegian Womens Public Health Association (NO)
- University of Pennsylvania (US)
Publication Details
- Journal
- Academic Radiology
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1016/j.acra.2025.01.035
- Primary Topic
- Melanoma and MAPK Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Yale University
- University of Pennsylvania
- Institute for Translational Medicine and Therapeutics
- National Cancer Center
- National Institutes of Health