Proportional Mean Residual Life Model With Varying Coefficients for Right Censored Data

The mean residual life provides the remaining life expectancy of a subject who has survived to a specific time point. This paper considers a proportional mean residual life model with varying coefficients, which allows one to explore the nonlinear interactions between some covariates and an exposure variable. In a semiparametric setting, we construct local estimating equations to obtain the varying coefficients and establish the asymptotic normality of the proposed estimators. Moreover, the weak convergence property for the local estimator of the baseline mean residual life function is developed. We conduct simulation studies to empirically examine the finite-sample performance of the proposed methods and apply the methodology to a real-life dataset on type 2 diabetic complications.

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Publication Details

Journal
Statistics in Medicine
Published
2025-02-19
DOI
https://doi.org/10.1002/sim.70008
Primary Topic
Statistical Methods and Inference
Type
article
Field-Weighted Citation Impact
0.00

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article

Proportional Mean Residual Life Model With Varying Coefficients for Right Censored Data

Xinyuan Song, Bing Wang, Qian Zhao
Statistics in Medicine
Statistical Methods and Inference
article

Proportional Mean Residual Life Model With Varying Coefficients for Right Censored Data

Xinyuan Song, Bing Wang, Qian Zhao
article en

Abstract

The mean residual life provides the remaining life expectancy of a subject who has survived to a specific time point. This paper considers a proportional mean residual life model with varying coefficients, which allows one to explore the nonlinear interactions between some covariates and an exposure variable. In a semiparametric setting, we construct local estimating equations to obtain the varying coefficients and establish the asymptotic normality of the proposed estimators. Moreover, the weak convergence property for the local estimator of the baseline mean residual life function is developed. We conduct simulation studies to empirically examine the finite-sample performance of the proposed methods and apply the methodology to a real-life dataset on type 2 diabetic complications.

Statistics in MedicineVol. 44(5)
Anhui University (CN), Chinese University of Hong Kong (HK), Shanghai University of International Business and Economics (CN)
National Natural Science Foundation of China, University Grants Committee
Openalex Percentile: Top 96%
Statistical Methods and Inference
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