Liver Fibrosis Regression in People Living With HIV After Successful Treatment for Hepatitis C

Most coinfected people with cirrhosis before HCV cure will remain cirrhotic. For those with significant fibrosis, regression can be expected within 2 years to levels not normally associated with an increased risk of end-stage liver disease. A TE measurement 2 years after cure should give a reliable estimate of residual fibrosis.

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Publication Details

Journal
JAIDS Journal of Acquired Immune Deficiency Syndromes
Published
2025-02-20
DOI
https://doi.org/10.1097/qai.0000000000003646
Primary Topic
Hepatitis C virus research
Type
article
Field-Weighted Citation Impact
0.00

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article

Liver Fibrosis Regression in People Living With HIV After Successful Treatment for Hepatitis C

Linda Wittkop, Margaret Elena Hellard, Marina B. Klein, Rachel Sacks‐Davis et al.
JAIDS Journal of Acquired Immune Deficiency Syndromes
Hepatitis C virus research
article

Liver Fibrosis Regression in People Living With HIV After Successful Treatment for Hepatitis C

Linda Wittkop, Margaret Elena Hellard, Marina B. Klein, Rachel Sacks‐Davis, Jim Young, Juan Berenguer, Ashleigh C. Stewart, Joseph Doyle, Gail Matthews, Daniela K van Santen, Karine Lacombe, Mark A Stoove, Shouao Wang, Andri Rauch, Marc van der Valk
article en

Abstract

Most coinfected people with cirrhosis before HCV cure will remain cirrhotic. For those with significant fibrosis, regression can be expected within 2 years to levels not normally associated with an increased risk of end-stage liver disease. A TE measurement 2 years after cure should give a reliable estimate of residual fibrosis.

JAIDS Journal of Acquired Immune Deficiency SyndromesVol. 99(2)
University of Bern (CH), Burnet Institute (AU), Université de Bordeaux (FR), Inserm (FR), University Hospital of Bern (CH), McGill University Health Centre (CA), Hospital General Universitario Gregorio Marañón (ES), UNSW Sydney (AU), Sorbonne Université (FR), Monash Alfred Psychiatry Research centre (AU), Bordeaux Population Health (FR), Stichting HIV Monitoring (NL), Centre de Recherche Saint-Antoine (FR), Institute of Infection and Immunity (CA), HIV Legal Network (CA), McGill University (CA)
National Science Foundation, Bristol-Myers Squibb, AstraZeneca, Gilead Sciences, Burnet Institute, ViiV Healthcare, Australian Government, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, Ministerie van Volksgezondheid, Welzijn en Sport, Ministerio de Ciencia e Innovación, Canadian Institutes of Health Research, Medical Research Council, National Health and Medical Research Council, Instituto de Salud Carlos III
Good health and well-being
Openalex Percentile: Top 95%
Hepatitis C virus research
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