Ultrasound speckle tracking imaging measurement of endocardial longitudinal strain for evaluation of prognostic value of “new quadruple” therapy in patients with chronic heart failure

Using 2D-STI layer-specific strain imaging to measure endocardial longitudinal strain serves as a significant non-invasive indicator in predicting MACEs during 1-year follow-up after "new quadruple" therapy in HFrEF patients with metabolic syndrome, highlighting substantial clinical applicability. Additionally, our findings suggest that the therapy may improve prognosis through the modulation of neuroendocrine mechanisms.