MS-275 facilitates osseointegration in osteoporotic rats by mitigating oxidative stress via activation of the miR-200a/Keap1/Nrf2 signaling pathway
MS-275 can reverse oxidative stress-induced cell damage, promote bone healing, and improve osteoporosis by activating the miRNA-200a/Keap1/Nrf2 pathway.
Authors
- Yuhu Chen
- Qiang Gu (ORCID: https://orcid.org/0000-0002-2606-0461)
- Wenkai Jiang (ORCID: https://orcid.org/0000-0002-2213-9850)
- Wengang Guan
- Junjie Yan (ORCID: https://orcid.org/0000-0001-6923-7936)
- Min Yang (ORCID: https://orcid.org/0000-0003-1231-3269)
- Bin Chen (ORCID: https://orcid.org/0000-0002-5485-2263)
- Jianqiao Li (ORCID: https://orcid.org/0000-0001-6145-424X)
- Zhi Zhou
Institutions
- First Affiliated Hospital of Wannan Medical College (CN)
Publication Details
- Journal
- Redox Report
- Published
- 2025-02-19
- DOI
- https://doi.org/10.1080/13510002.2025.2466142
- Citations
- 3
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 2.81