The intestinal microbiota modulates the visceral sensitivity involved in IBS induced by restraint combined with tail clustering
1. The restraint combined with the tail clamp stress method is superior among the three stress protocols and successfully induces the IBS mouse model. 2. <i>Acinetobacte</i>r and <i>Akkermansia</i> may contribute to the development of IBS induced by restraint combined with tail clamp stress through the regulation of SCFAs and 5-HT.
Authors
- Junxi Shen (ORCID: https://orcid.org/0000-0003-1653-4966)
- Hui Peng (ORCID: https://orcid.org/0000-0001-9901-5955)
- Na Deng (ORCID: https://orcid.org/0000-0002-4557-5372)
- Xiaoyuan Lin (ORCID: https://orcid.org/0000-0002-3361-0126)
- Qin Liu (ORCID: https://orcid.org/0000-0002-9282-0238)
- Leyao Fang (ORCID: https://orcid.org/0000-0002-8226-2017)
- Shao-Hua Xie (ORCID: https://orcid.org/0000-0003-0864-8154)
Institutions
- Hunan University of Traditional Chinese Medicine (CN)
- First Affiliated Hospital of Hunan University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-02-20
- DOI
- https://doi.org/10.3389/fcimb.2025.1549617
- Citations
- 2
- Primary Topic
- Gastrointestinal motility and disorders
- Type
- article
- Field-Weighted Citation Impact
- 3.62
Funders
- Natural Science Foundation of Hunan Province