The clinical value of α-hydroxybutyrate dehydrogenase, cardiac troponin I, and B-type natriuretic peptide in perioperative diagnosis of heart failure in children with congenital heart disease
In children with CHD, preoperative levels of α-HBDH, cTnI, and BNP during the perioperative period are closely correlated with cardiac function, significantly increasing with the severity of cardiac dysfunction. These biomarkers have important clinical value for diagnosing heart failure, with the combined detection of cTnI and BNP demonstrating the highest diagnostic efficacy.
Authors
- Xianmin Wang (ORCID: https://orcid.org/0000-0003-3480-8780)
- Jun-Hong Shen (ORCID: https://orcid.org/0000-0002-6220-096X)
- Jun Yin (ORCID: https://orcid.org/0000-0002-6297-4121)
- Tao Yuan
- Junru Wang (ORCID: https://orcid.org/0000-0003-1967-5967)
- Shuqiong Xu
- Shihua Huang
- Qingsong Wang (ORCID: https://orcid.org/0000-0002-4133-8724)
- Tongyong Luo
Institutions
- Chengdu Medical College (CN)
- Sichuan University (CN)
- Chengdu Women's and Children's Central Hospital (CN)
- Mianyang Central Hospital (CN)
Publication Details
- Journal
- Frontiers in Pediatrics
- Published
- 2025-02-20
- DOI
- https://doi.org/10.3389/fped.2025.1502439
- Citations
- 3
- Primary Topic
- Cardiovascular Function and Risk Factors
- Type
- article
- Field-Weighted Citation Impact
- 4.16