Interacting and joint effects of frailty and inflammation on cardiovascular disease risk and the mediating role of inflammation in middle-aged and elderly populations
Inflammation may amplify the harmful effect of frailty on the incidence of CVDs. Improving frailty alone might not substantially reduce the risk of CVDs, but effectively controlling inflammation might help to reduce the negative effects of frailty on cardiovascular health.
Authors
- Xuefei Hou (ORCID: https://orcid.org/0000-0001-8380-5055)
- Shicai Ye (ORCID: https://orcid.org/0009-0005-7663-7379)
- Suru Yue (ORCID: https://orcid.org/0000-0002-3198-5952)
- Jiayuan Wu (ORCID: https://orcid.org/0000-0002-5064-1944)
- Xiao Lin Li (ORCID: https://orcid.org/0000-0002-2534-1392)
- Jia Wang (ORCID: https://orcid.org/0000-0003-1963-2799)
- Zihan Xu (ORCID: https://orcid.org/0000-0001-5499-4803)
- Yingbai Wang
Institutions
- Guangdong Medical College (CN)
- Affiliated Hospital of Guangdong Medical College Hospital (CN)
Publication Details
- Journal
- BMC Cardiovascular Disorders
- Published
- 2025-02-20
- DOI
- https://doi.org/10.1186/s12872-025-04567-1
- Citations
- 9
- Primary Topic
- Frailty in Older Adults
- Type
- article
- Field-Weighted Citation Impact
- 11.02