The Effect of Medication Therapy Management (MTM) on Adherence and Quality of Life of Hypertension Patients in Puskesmas Banyumas Regency

Background: Hypertension is one of the most common cardiovascular diseases in Indonesia and in the world. Hypertension requires a long-term treatment process, and compliance in taking medication is needed for blood and to improve patients' quality of life. Medication Therapy Management (MTM) is a pharmaceutical service method that can enhance individual hypertension patient compliance. This study aims to determine the effect of pharmaceutical services based on Medication Therapy Management (MTM) on hypertensive patients' adherence and quality of life at the Health Center in Banyumas Regency. Methods: This research is an experimental method used in Randomized Controlled Trials (RCT). The variable measured was patient compliance with pill counts, while the quality of life was measured with the EQ-5D-5L questionnaire. Data collection will take place one month after the first data collection. Data were analyzed statistically using the Wilcoxon test to determine differences in results before and after the intervention. Results: This study was attended by 180 people. Most of the respondents were female (90%), the average age was 55-64 years (44.4%), the average education was an elementary school (70%), and the length of time the patient had suffered from hypertension was 3 years at most (33,3%). The highest number of drugs received by respondents was one type of drug (43.3%), more respondents were without comorbidities (84.4%), and more respondents were working (60%). Pharmaceutical services based on Medication Therapy Management (MTM) at the Health Center in Banyumas Regency have been proven to be able to increase the compliance level of hypertensive patients, namely 0.54 ± -0.353 with a p-value of 0.000 and have been proven to improve the quality of life of hypertensive patients, namely 5.38 ± 2.962 with a p-value of 0.000. Conclusion: Medication Therapy Management (MTM) has a significant influence on increasing hypertensive patients’ adherence and quality of life. Keywords: Adherence, Hypertension, Medication Therapy Management, Quality of Life.