Biofunctionalization of silk fibroin scaffolds with enamel matrix protein and injectable platelet rich fibrin for soft tissue augmentation: an in-ovo study
Biofunctionalization with iPRF in CM leads to a high vascularization rate probably through their capability of retaining higher liquid volumes, suggesting improved intraoral wound healing after guided tissue regeneration (GTR). Despite biofunctionalization, SF matrices exhibit a high vascularization, indicating SF as a promising material for GTR.
Authors
- Andreas Pabst (ORCID: https://orcid.org/0000-0003-4841-7203)
- Sandra Fuest (ORCID: https://orcid.org/0009-0006-4083-452X)
- Nadine Wiesmann (ORCID: https://orcid.org/0000-0001-5661-6953)
- Philipp Becker (ORCID: https://orcid.org/0009-0004-6253-0944)
- Ralf Smeets
- Sebastian Blatt (ORCID: https://orcid.org/0000-0003-1949-4605)
- Jürgen Brieger
- Peer W. Kämmerer (ORCID: https://orcid.org/0000-0002-1671-3764)
- Diana Heimes (ORCID: https://orcid.org/0000-0001-9899-7715)
- Timpe Heidebrecht
Institutions
- Universität Hamburg (DE)
- Johannes Gutenberg University Mainz (DE)
- University Medical Center of the Johannes Gutenberg University Mainz (DE)
- University Medical Center Hamburg-Eppendorf (DE)
- Bundeswehrzentralkrankenhaus Koblenz (DE)
Publication Details
- Journal
- International Journal of Implant Dentistry
- Published
- 2025-02-20
- DOI
- https://doi.org/10.1186/s40729-025-00601-1
- Primary Topic
- Silk-based biomaterials and applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universitätsmedizin der Johannes Gutenberg-Universität Mainz