Novel Biomarkers for the Early Detection of Myocardial Infarction

Early detection of myocardial infarction (MI) is essential, yet traditional biomarkers like Troponin and CK-MB have limited sensitivity in the initial hours after symptom onset. Emerging biomarkers such as miRNA-208, miRNA-499, and Copeptin show promise for earlier diagnosis, particularly within the first 3 hours. Additionally, markers like GDF-15, sST2, suPAR, H-FABP, sLOX-1, and various RNAs (including N1LR, SNHG1, TTTY15, and HULC) offer potential for improved MI detection and prognostic assessment. Integrating these novel biomarkers could enhance early diagnosis and management of MI, ultimately leading to better patient outcomes.

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Publication Details

Journal
Journal of Science Technology Education Art and Medicine
Published
2024-12-23
DOI
https://doi.org/10.63137/jsteam.650859
Primary Topic
Cardiac Fibrosis and Remodeling
Type
article
Field-Weighted Citation Impact
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article

Novel Biomarkers for the Early Detection of Myocardial Infarction

Omar Alqahtani, Zeeshan Ahmed, Kalpana Singh, Mohammad Ayaz Khan
Journal of Science Technology Education Art and Medicine
Cardiac Fibrosis and Remodeling
article

Novel Biomarkers for the Early Detection of Myocardial Infarction

Omar Alqahtani, Zeeshan Ahmed, Kalpana Singh, Mohammad Ayaz Khan
article en

Abstract

Early detection of myocardial infarction (MI) is essential, yet traditional biomarkers like Troponin and CK-MB have limited sensitivity in the initial hours after symptom onset. Emerging biomarkers such as miRNA-208, miRNA-499, and Copeptin show promise for earlier diagnosis, particularly within the first 3 hours. Additionally, markers like GDF-15, sST2, suPAR, H-FABP, sLOX-1, and various RNAs (including N1LR, SNHG1, TTTY15, and HULC) offer potential for improved MI detection and prognostic assessment. Integrating these novel biomarkers could enhance early diagnosis and management of MI, ultimately leading to better patient outcomes.

Journal of Science Technology Education Art and MedicineVol. 1(2)
King Edward Medical University (PK), Hamad Medical Corporation (QA)
Good health and well-being
Openalex Percentile: Top 54%
Cardiac Fibrosis and Remodeling
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