Cerebral oxygenation and hemodynamic changes during ephedrine and phenylephrine administration for transient intraoperative hypotension in patients undergoing major abdominal surgery: a randomized controlled trial
In the management of intraoperative hypotension, both phenylephrine and ephedrine effectively increase MAP and MCAvm, albeit with their differential effects on CO and HR. It seems that neither vasopressor has a significant impact on cerebral oxygenation and cerebral autoregulation.
Authors
- Jun Zhang
- Xueyan Li (ORCID: https://orcid.org/0000-0002-4009-6348)
- Yijun Zheng (ORCID: https://orcid.org/0000-0002-0163-6401)
Institutions
- Shanghai Medical College of Fudan University (CN)
- Fudan University Shanghai Cancer Center (CN)
Publication Details
- Journal
- BMC Anesthesiology
- Published
- 2025-02-20
- DOI
- https://doi.org/10.1186/s12871-025-02944-z
- Citations
- 1
- Primary Topic
- Hemodynamic Monitoring and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- Science and Technology Innovation Plan Of Shanghai Science and Technology Commission